… two Sen1 mutants, while fast Pol II transcription exacerbates these phenotypes. Our findings
indicate that a balance between Pol II … the window for efficient termination. Perturbations of …

… for Sen1-dependent termination and poly(A)-dependent termination is broadly available
to target Pol II … is likely to be determined by kinetic competition between phosphorylation-specific …

… Last, we also observed Sen1-dependent release of RNAPIIIs that are paused at sequences
other than T-tracts, for instance, at pausing sites upstream of the canonical terminators, …

… termination of RNAPIII transcription in budding yeast. In this study, to address specifically
the function of Sen1 in RNAPIII transcription termination … Eukaryotic RNA polymerase II (RNAPII…

… options and that there may be an ongoing competition between termination machineries for
… kinetics of transcription elongation (140) or the interaction between Sen1 and the CTD (99). …

… transcription termination at a subset of RNA polymerase II genes. Whether Senataxin also
contributes to transcription termination at … efficient Sen1-dependent transcription termination …

… to the RNA polymerase II (RNAPII) for efficient termination. We … Sen1-dependent transcription
termination and a rationale for the kinetic competition between elongation and termination…

… As shown in Figure 6D, H3K4me2 levels decreased in HU-treated sen1 URL mutants
relative to WT, while the inactivation of Spt2 partially rescued such sen1-dependent defect. …

… Transcription termination occurs when the RNA polymerase (… Efficient transcription termination
is crucial not only for the … of transcription termination factors with the RNA polymerase II …

… Transcription by RNA polymerase II involves the CTD of its largest subunit, but the role of
this … 0 end of genes and that this pause promotes termination of small non-coding RNAs. …